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Meta-analysis of pharmacogenetic interactions in amyotrophic lateral sclerosis clinical trials
OBJECTIVE: To assess whether genetic subgroups in recent amyotrophic lateral sclerosis (ALS) trials responded to treatment with lithium carbonate, but that the treatment effect was lost in a large cohort of nonresponders. METHODS: Individual participant data were obtained from 3 randomized trials in...
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| Wydane w: | Neurology |
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| Główni autorzy: | , , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Lippincott Williams & Wilkins
2017
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5664299/ https://ncbi.nlm.nih.gov/pubmed/28978660 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000004606 |
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