Refining eligibility criteria for amyotrophic lateral sclerosis clinical trials

OBJECTIVE: To assess the effect of eligibility criteria on exclusion rates, generalizability, and outcome heterogeneity in amyotrophic lateral sclerosis (ALS) clinical trials and to assess the value of a risk-based inclusion criterion. METHODS: A literature search was performed to summarize the elig...

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Vydáno v:Neurology
Hlavní autoři: van Eijk, Ruben P.A., Westeneng, Henk-Jan, Nikolakopoulos, Stavros, Verhagen, Iris E., van Es, Michael A., Eijkemans, Marinus J.C., van den Berg, Leonard H.
Médium: Artigo
Jazyk:Inglês
Vydáno: Lippincott Williams & Wilkins 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6369899/
https://ncbi.nlm.nih.gov/pubmed/30626653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000006855
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