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Elucidation of Lipid Binding Sites on Lung Surfactant Protein A using X-ray Crystallography, Mutagenesis and Molecular Dynamics Simulations()
Surfactant protein A (SP-A) is a collagenous C-type lectin (collectin) that is critical for pulmonary defense against inhaled microorganisms. Bifunctional avidity of SP-A for pathogen associated molecular patterns (PAMPs) such as lipid A and for dipalmitoylphosphatidylcholine (DPPC), the major compo...
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| Publicado no: | Biochemistry |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5663190/ https://ncbi.nlm.nih.gov/pubmed/27324153 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00048 |
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