Crystallographic Complexes of Surfactant Protein A and Carbohydrates Reveal Ligand-induced Conformational Change

Surfactant protein A (SP-A), a C-type lectin, plays an important role in innate lung host defense against inhaled pathogens. Crystallographic SP-A·ligand complexes have not been reported to date, limiting available molecular information about SP-A interactions with microbial surface components. This...

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Hlavní autoři: Shang, Feifei, Rynkiewicz, Michael J., McCormack, Francis X., Wu, Huixing, Cafarella, Tanya M., Head, James F., Seaton, Barbara A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2011
Témata:
Molecular Biophysics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3013034/
https://ncbi.nlm.nih.gov/pubmed/21047777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.175265
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