Surfactant Protein A Modulates Cell Surface Expression of CR3 on Alveolar Macrophages and Enhances CR3-mediated Phagocytosis

Pulmonary surfactant protein A (SP-A), a member of the collectin family, plays an important role in innate immune defense of the lung. In this study, we examined the role of SP-A in modulating complement receptor-mediated phagocytosis. Complement receptors (CR), CR3 (CD11b), and CR4 (CD11c) were exp...

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Bibliografiske detaljer
Main Authors: Gil, Malgorzata, McCormack, Francis X., LeVine, Ann Marie
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2009
Fag:
Molecular Basis of Cell and Developmental Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2658045/
https://ncbi.nlm.nih.gov/pubmed/19155216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808643200
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