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Noncanonical regulation of insulin-mediated ERK activation by phosphoinositide 3-kinase γ

Classically Class IB phosphoinositide 3-kinase (PI3Kγ) plays a role in extracellular signal–regulated kinase (ERK) activation following G-protein coupled receptor (GPCR) activation. Knock-down of PI3Kγ unexpectedly resulted in loss of ERK activation to receptor tyrosine kinase agonists such as epide...

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Publicado en:Mol Biol Cell
Autores principales: Mohan, Maradumane L., Chatterjee, Arunachal, Ganapathy, Swetha, Mukherjee, Sromona, Srikanthan, Sowmya, Jolly, George P., Anand, Rohit S., Prasad, Sathyamangla V. Naga
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Cell Biology 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5662266/
https://ncbi.nlm.nih.gov/pubmed/28877982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-12-0864
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