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Noncanonical regulation of insulin-mediated ERK activation by phosphoinositide 3-kinase γ
Classically Class IB phosphoinositide 3-kinase (PI3Kγ) plays a role in extracellular signal–regulated kinase (ERK) activation following G-protein coupled receptor (GPCR) activation. Knock-down of PI3Kγ unexpectedly resulted in loss of ERK activation to receptor tyrosine kinase agonists such as epide...
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| Publicado no: | Mol Biol Cell |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5662266/ https://ncbi.nlm.nih.gov/pubmed/28877982 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-12-0864 |
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