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Phosphorylation of Src by phosphoinositide 3-kinase regulates beta-adrenergic receptor mediated EGFR transactivation
β(2)-adrenergic receptors (β(2)AR) transactivate epidermal growth factor receptors (EGFR) through formation of a β(2)AR-EGFR complex that requires activation of Src to mediate signaling. Here, we show that both lipid and protein kinase activities of the bifunctional phosphoinositide 3-kinase (PI3K)...
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| Veröffentlicht in: | Cell Signal |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4980165/ https://ncbi.nlm.nih.gov/pubmed/27169346 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2016.05.006 |
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