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Phosphorylation of Src by phosphoinositide 3-kinase regulates beta-adrenergic receptor mediated EGFR transactivation
β(2)-adrenergic receptors (β(2)AR) transactivate epidermal growth factor receptors (EGFR) through formation of a β(2)AR-EGFR complex that requires activation of Src to mediate signaling. Here, we show that both lipid and protein kinase activities of the bifunctional phosphoinositide 3-kinase (PI3K)...
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| Publicat a: | Cell Signal |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4980165/ https://ncbi.nlm.nih.gov/pubmed/27169346 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2016.05.006 |
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