Phosphoinositide 3-Kinase γ Inhibits Cardiac GSK-3 Independently of Akt

Activation of cardiac phosphoinositide 3-kinase a (PI3Kα) by growth factors, such as insulin, or activation of PI3Kγ downstream of heterotrimeric guanine nucleotide–binding protein (G protein)–coupled receptors stimulates the activity of the kinase Akt, which phosphorylates and inhibits glycogen syn...

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Bibliografiska uppgifter
Huvudupphovsmän: Mohan, Maradumane L., Jha, Babal K., Gupta, Manveen K., Vasudevan, Neelakantan T., Martelli, Elizabeth E., Mosinski, John David, Naga Prasad, Sathyamangla V.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3967506/
https://ncbi.nlm.nih.gov/pubmed/23354687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2003308
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