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Phosphoinositide 3-Kinase γ Inhibits Cardiac GSK-3 Independently of Akt
Activation of cardiac phosphoinositide 3-kinase a (PI3Kα) by growth factors, such as insulin, or activation of PI3Kγ downstream of heterotrimeric guanine nucleotide–binding protein (G protein)–coupled receptors stimulates the activity of the kinase Akt, which phosphorylates and inhibits glycogen syn...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3967506/ https://ncbi.nlm.nih.gov/pubmed/23354687 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2003308 |
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