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G-Protein Coupled Receptor Resensitization – Appreciating the Balancing Act of Receptor Function

G-protein coupled receptors (GPCRs) are seven transmembrane receptors that are pivotal regulators of cellular responses including vision, cardiac contractility, olfaction, and platelet activation. GPCRs have been a major target for drug discovery due to their role in regulating a broad range of phys...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Curr Mol Pharmacol
Hauptverfasser: Mohan, Maradumane L., Vasudevan, Neelakantan T., Gupta, Manveen K., Martelli, Elizabeth E., Prasad, Sathyamangla V. Naga
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4607669/
https://ncbi.nlm.nih.gov/pubmed/22697395
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