G(βγ) Independent Recruitment of G-Protein Coupled Receptor Kinase 2 Drives TNFα-Induced Cardiac Beta-Adrenergic Receptor Dysfunction

BACK GROUND: Pro-inflammatory cytokine tumor necrosis factor α (TNFα) induces β-adrenergic receptor (βAR) desensitization, but mechanisms proximal to the receptor in contributing to cardiac dysfunction are not known. METHODS AND RESULTS: Two different pro-inflammatory transgenic mouse models with ca...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Vasudevan, Neelakantan T., Mohan, Maradumane L., Gupta, Manveen K., Martelli, Elizabeth E., Hussain, Afshan K., Qin, Yilu, Chandrasekharan, Unni M., Young, David, Feldman, Arthur M., Sen, Subha, Dorn, Gerald W., DiCorleto, Paul E., Naga Prasad, Sathyamangla V.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874808/
https://ncbi.nlm.nih.gov/pubmed/23785004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.113.003183
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares