G(βγ) Independent Recruitment of G-Protein Coupled Receptor Kinase 2 Drives TNFα-Induced Cardiac Beta-Adrenergic Receptor Dysfunction

BACK GROUND: Pro-inflammatory cytokine tumor necrosis factor α (TNFα) induces β-adrenergic receptor (βAR) desensitization, but mechanisms proximal to the receptor in contributing to cardiac dysfunction are not known. METHODS AND RESULTS: Two different pro-inflammatory transgenic mouse models with ca...

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Bibliografski detalji
Glavni autori: Vasudevan, Neelakantan T., Mohan, Maradumane L., Gupta, Manveen K., Martelli, Elizabeth E., Hussain, Afshan K., Qin, Yilu, Chandrasekharan, Unni M., Young, David, Feldman, Arthur M., Sen, Subha, Dorn, Gerald W., DiCorleto, Paul E., Naga Prasad, Sathyamangla V.
Format: Artigo
Jezik:Inglês
Izdano: 2013
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874808/
https://ncbi.nlm.nih.gov/pubmed/23785004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.113.003183
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