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Squamous cell transformation and EGFR T790M mutation as acquired resistance mechanisms in a patient with lung adenocarcinoma treated with a tyrosine kinase inhibitor: A case report

The present case report describes the infrequent coexistence of squamous cell transformation and the epidermal growth factor receptor (EGFR) T790M mutation as resistance mechanisms to first line treatment with tyrosine kinase inhibitors. The patient was a 44-year-old female, diagnosed with a primiti...

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Vydáno v:Oncol Lett
Hlavní autoři: Bruno, Rossella, Proietti, Agnese, Alì, Greta, Puppo, Gianfranco, Ribechini, Alessandro, Chella, Antonio, Fontanini, Gabriella
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5661389/
https://ncbi.nlm.nih.gov/pubmed/29113230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.6913
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