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Squamous cell transformation and EGFR T790M mutation as acquired resistance mechanisms in a patient with lung adenocarcinoma treated with a tyrosine kinase inhibitor: A case report

The present case report describes the infrequent coexistence of squamous cell transformation and the epidermal growth factor receptor (EGFR) T790M mutation as resistance mechanisms to first line treatment with tyrosine kinase inhibitors. The patient was a 44-year-old female, diagnosed with a primiti...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: Bruno, Rossella, Proietti, Agnese, Alì, Greta, Puppo, Gianfranco, Ribechini, Alessandro, Chella, Antonio, Fontanini, Gabriella
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5661389/
https://ncbi.nlm.nih.gov/pubmed/29113230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.6913
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