Multiple Resistance Mechanisms to Tyrosine Kinase Inhibitors in EGFR Mutated Lung Adenocarcinoma: A Case Report Harboring EGFR Mutations, MET Amplification, and Squamous Cell Transformation

Resistance to EGFR tyrosin kinase inhibitors (TKI) inevitably occurs. Here it is reported the case of a young patient affected by lung adenocarcinoma harboring the L858R EGFR sensitive mutation. The patient developed multiple TKI resistance mechanisms: T790M EGFR resistance mutation, detected only o...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Bruno, Rossella, Del Re, Marzia, Cucchiara, Federico, Petrini, Iacopo, Alì, Greta, Crucitta, Stefania, Proietti, Agnese, Valleggi, Simona, Chella, Antonio, Danesi, Romano, Fontanini, Gabriella
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8226241/
https://ncbi.nlm.nih.gov/pubmed/34178662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.674604
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados