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Pharmacological preconditioning with gemfibrozil preserves cardiac function after heart transplantation
While heart transplantation (HTX) is the definitive therapy of heart failure, donor shortage is emerging. Pharmacological activation of soluble guanylate cyclase (sGC) and increased cGMP-signalling have been reported to have cardioprotective properties. Gemfibrozil has recently been shown to exert s...
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| Veröffentlicht in: | Sci Rep |
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| Hauptverfasser: | , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5660179/ https://ncbi.nlm.nih.gov/pubmed/29079777 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14587-3 |
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