Prevention of the development of heart failure with preserved ejection fraction by the phosphodiesterase‐5A inhibitor vardenafil in rats with type 2 diabetes

AIMS: Heart failure with preserved ejection fraction (HFpEF) has a great epidemiological burden. The pathophysiological role of cyclic guanosine monophosphate (cGMP) signalling has been intensively investigated in HFpEF. Elevated levels of cGMP have been shown to exert cardioprotective effects in va...

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Detalhes bibliográficos
Publicado no:Eur J Heart Fail
Main Authors: Mátyás, Csaba, Németh, Balázs T., Oláh, Attila, Török, Marianna, Ruppert, Mihály, Kellermayer, Dalma, Barta, Bálint A., Szabó, Gábor, Kökény, Gábor, Horváth, Eszter M., Bódi, Beáta, Papp, Zoltán, Merkely, Béla, Radovits, Tamás
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2016
Assuntos:
Pathophysiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5347963/
https://ncbi.nlm.nih.gov/pubmed/27995696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ejhf.711
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