The soluble guanylate cyclase activator cinaciguat prevents cardiac dysfunction in a rat model of type-1 diabetes mellitus

BACKGROUND: Diabetes mellitus (DM) leads to the development of diabetic cardiomyopathy, which is associated with altered nitric oxide (NO)—soluble guanylate cyclase (sGC)—cyclic guanosine monophosphate (cGMP) signalling. Cardioprotective effects of elevated intracellular cGMP-levels have been descri...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Cardiovasc Diabetol
मुख्य लेखकों: Mátyás, Csaba, Németh, Balázs Tamás, Oláh, Attila, Hidi, László, Birtalan, Ede, Kellermayer, Dalma, Ruppert, Mihály, Korkmaz-Icöz, Sevil, Kökény, Gábor, Horváth, Eszter Mária, Szabó, Gábor, Merkely, Béla, Radovits, Tamás
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: BioMed Central 2015
विषय:
Original Investigation
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4628236/
https://ncbi.nlm.nih.gov/pubmed/26520063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12933-015-0309-x
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