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Cinaciguat prevents the development of pathologic hypertrophy in a rat model of left ventricular pressure overload
Pathologic myocardial hypertrophy develops when the heart is chronically pressure-overloaded. Elevated intracellular cGMP-levels have been reported to prevent the development of pathologic myocardial hypertrophy, therefore we investigated the effects of chronic activation of the cGMP producing enzym...
Shranjeno v:
| izdano v: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2016
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5112572/ https://ncbi.nlm.nih.gov/pubmed/27853261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep37166 |
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