Pharmacological preconditioning with gemfibrozil preserves cardiac function after heart transplantation

While heart transplantation (HTX) is the definitive therapy of heart failure, donor shortage is emerging. Pharmacological activation of soluble guanylate cyclase (sGC) and increased cGMP-signalling have been reported to have cardioprotective properties. Gemfibrozil has recently been shown to exert s...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Benke, Kálmán, Mátyás, Csaba, Sayour, Alex Ali, Oláh, Attila, Németh, Balázs Tamás, Ruppert, Mihály, Szabó, Gábor, Kökény, Gábor, Horváth, Eszter Mária, Hartyánszky, István, Szabolcs, Zoltán, Merkely, Béla, Radovits, Tamás
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5660179/
https://ncbi.nlm.nih.gov/pubmed/29079777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14587-3
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