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Importance of the REM (Ras exchange) domain for membrane interactions by RasGRP3
RasGRP comprises a family of guanine nucleotide exchange factors, regulating the dissociation of GDP from Ras GTPases to enhance the formation of the active GTP-bound form. RasGRP1 possesses REM (Ras exchange), GEF (catalytic), EF-hand, C1, SuPT (suppressor of PT), and PT (plasma membrane-targeting)...
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| Udgivet i: | Biochim Biophys Acta |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5659902/ https://ncbi.nlm.nih.gov/pubmed/28912101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2017.09.010 |
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