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Importance of the REM (Ras exchange) domain for membrane interactions by RasGRP3

RasGRP comprises a family of guanine nucleotide exchange factors, regulating the dissociation of GDP from Ras GTPases to enhance the formation of the active GTP-bound form. RasGRP1 possesses REM (Ras exchange), GEF (catalytic), EF-hand, C1, SuPT (suppressor of PT), and PT (plasma membrane-targeting)...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Biochim Biophys Acta
Main Authors: Czikora, Agnes, Kedei, Noemi, Kalish, Heather, Blumberg, Peter M.
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5659902/
https://ncbi.nlm.nih.gov/pubmed/28912101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2017.09.010
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