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RasGRP Ras guanine nucleotide exchange factors in cancer

RasGRP proteins are activators of Ras and other related small GTPases by the virtue of functioning as guanine nucleotide exchange factors (GEFs). In vertebrates, four RasGRP family members have been described. RasGRP-1 through −4 share many structural domains but there are also subtle differences be...

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Bibliographic Details
Main Authors: Ksionda, Olga, Limnander, Andre, Roose, Jeroen P.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3987922/
https://ncbi.nlm.nih.gov/pubmed/24744772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11515-013-1276-9
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