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Src-family kinases negatively regulate NFAT signaling in resting human T cells

T cell signaling is required for activation of both natural and therapeutic T cells including chimeric antigen receptor (CAR) T cells. Identification of novel factors and pathways regulating T cell signaling may aid in development of effective T cell therapies. In resting human T cells, the majority...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Baer, Alan, Colon-Moran, Winston, Xiang, Jinhua, Stapleton, Jack T., Bhattarai, Nirjal
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5658144/
https://ncbi.nlm.nih.gov/pubmed/29073235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0187123
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