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Src-family kinases negatively regulate NFAT signaling in resting human T cells

T cell signaling is required for activation of both natural and therapeutic T cells including chimeric antigen receptor (CAR) T cells. Identification of novel factors and pathways regulating T cell signaling may aid in development of effective T cell therapies. In resting human T cells, the majority...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Baer, Alan, Colon-Moran, Winston, Xiang, Jinhua, Stapleton, Jack T., Bhattarai, Nirjal
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5658144/
https://ncbi.nlm.nih.gov/pubmed/29073235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0187123
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