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Characterization of the effects of immunomodulatory drug fingolimod (FTY720) on human T cell receptor signaling pathways

Immune responses against gene therapy products limit its therapeutic efficacy and present a safety risk. Identification of agents that blunt immune reactions may aid in developing novel immunomodulatory therapies. Fingolimod (FTY720) is an FDA approved immunomodulatory drug for treating multiple scl...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Baer, Alan, Colon-Moran, Winston, Bhattarai, Nirjal
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6053412/
https://ncbi.nlm.nih.gov/pubmed/30026610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-29355-0
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