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GB virus C envelope protein E2 inhibits T cell receptor induced IL-2 production and alters IL-2 signaling pathways
GB virus type C (GBV-C) viremia is associated with reduced CD4+ T cell expansion following Interleukin 2 (IL-2) therapy and with a reduction in T cell activation in HIV-infected individuals. Mechanism(s) by which GBV-C might alter T-cell activation or IL-2 signaling have not been studied. Here, we a...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3424397/ https://ncbi.nlm.nih.gov/pubmed/22844114 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201324 |
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