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miR25/93 mediates hypoxia-induced immunosuppression by repressing cGAS
The mechanisms by which hypoxic tumors evade immunological pressure and anti-tumor immunity remain elusive. Here, we report that two hypoxia-responsive microRNAs, miR25 and miR93, are important for establishing an immunosuppressive tumor microenvironment by down-regulating expression of the DNA-sens...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Nat Cell Biol |
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| Κύριοι συγγραφείς: | , , , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2017
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5658024/ https://ncbi.nlm.nih.gov/pubmed/28920955 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3615 |
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