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Hypoxia, Epithelial-Mesenchymal Transition, and TET-Mediated Epigenetic Changes
Tumor hypoxia is a pathophysiologic outcome of disrupted microcirculation with inadequate supply of oxygen, leading to enhanced proliferation, epithelial-mesenchymal transition (EMT), metastasis, and chemo-resistance. Epigenetic changes induced by hypoxia are well documented, and they lead to tumor...
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| Publicado no: | J Clin Med |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4773780/ https://ncbi.nlm.nih.gov/pubmed/26861406 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm5020024 |
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