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Epigenetics, TET proteins, and hypoxia in epithelial-mesenchymal transition and tumorigenesis

Hypoxia in tumors is primarily a pathophysiologic consequence of structurally and functionally disturbed microcirculation with inadequate supply of oxygen. Tumor hypoxia is strongly associated with tumor propagation, malignant progression, and resistance to therapy. Aberrant epigenetic regulation pl...

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Bibliografiske detaljer
Udgivet i:Biomedicine (Taipei)
Main Authors: Chen, Hsiao-Fan, Wu, Kou-Juey
Format: Artigo
Sprog:Inglês
Udgivet: China Medical University 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4751095/
https://ncbi.nlm.nih.gov/pubmed/26869355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7603/s40681-016-0001-9
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