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Epigenetics, TET proteins, and hypoxia in epithelial-mesenchymal transition and tumorigenesis

Hypoxia in tumors is primarily a pathophysiologic consequence of structurally and functionally disturbed microcirculation with inadequate supply of oxygen. Tumor hypoxia is strongly associated with tumor propagation, malignant progression, and resistance to therapy. Aberrant epigenetic regulation pl...

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Detalhes bibliográficos
Publicado no:Biomedicine (Taipei)
Main Authors: Chen, Hsiao-Fan, Wu, Kou-Juey
Formato: Artigo
Idioma:Inglês
Publicado em: China Medical University 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4751095/
https://ncbi.nlm.nih.gov/pubmed/26869355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7603/s40681-016-0001-9
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