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Epigenetics, TET proteins, and hypoxia in epithelial-mesenchymal transition and tumorigenesis

Hypoxia in tumors is primarily a pathophysiologic consequence of structurally and functionally disturbed microcirculation with inadequate supply of oxygen. Tumor hypoxia is strongly associated with tumor propagation, malignant progression, and resistance to therapy. Aberrant epigenetic regulation pl...

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Bibliographische Detailangaben
Veröffentlicht in:Biomedicine (Taipei)
Hauptverfasser: Chen, Hsiao-Fan, Wu, Kou-Juey
Format: Artigo
Sprache:Inglês
Veröffentlicht: China Medical University 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4751095/
https://ncbi.nlm.nih.gov/pubmed/26869355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7603/s40681-016-0001-9
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