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Hypoxia-regulated target genes implicated in tumor metastasis

Hypoxia is an important microenvironmental factor that induces cancer metastasis. Hypoxia/hypoxia-inducible factor-1α (HIF-1α) regulates many important steps of the metastatic processes, especially epithelial-mesenchymal transition (EMT) that is one of the crucial mechanisms to cause early stage of...

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Autores principales: Tsai, Ya-Ping, Wu, Kou-Juey
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3541338/
https://ncbi.nlm.nih.gov/pubmed/23241400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-19-102
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