α-Lipoic acid treatment prevents cystine urolithiasis in a mouse model of cystinuria

Cystinuria is an incompletely dominant disorder characterized by defective urinary cystine reabsorption that results in the formation of cystine-based urinary stones. Current treatment options are limited in their effectiveness at preventing stone recurrence and often poorly tolerated. We report tha...

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Vydáno v:Nat Med
Hlavní autoři: Zee, Tiffany, Bose, Neelanjan, Zee, Jarcy, Beck, Jennifer N., Yang, See, Parihar, Jaspreet, Yang, Min, Damodar, Sruthi, Hall, David, O’Leary, Monique N., Ramanathan, Arvind, Gerona, Roy R., Killilea, David W., Chi, Thomas, Tischfield, Jay, Sahota, Amrik, Kahn, Arnold, Stoller, Marshall L., Kapahi, Pankaj
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5656064/
https://ncbi.nlm.nih.gov/pubmed/28165480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.4280
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