α-Lipoic acid treatment prevents cystine urolithiasis in a mouse model of cystinuria

Cystinuria is an incompletely dominant disorder characterized by defective urinary cystine reabsorption that results in the formation of cystine-based urinary stones. Current treatment options are limited in their effectiveness at preventing stone recurrence and often poorly tolerated. We report tha...

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Publicado no:Nat Med
Main Authors: Zee, Tiffany, Bose, Neelanjan, Zee, Jarcy, Beck, Jennifer N., Yang, See, Parihar, Jaspreet, Yang, Min, Damodar, Sruthi, Hall, David, O’Leary, Monique N., Ramanathan, Arvind, Gerona, Roy R., Killilea, David W., Chi, Thomas, Tischfield, Jay, Sahota, Amrik, Kahn, Arnold, Stoller, Marshall L., Kapahi, Pankaj
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5656064/
https://ncbi.nlm.nih.gov/pubmed/28165480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.4280
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