Novel cystine ester mimics for the treatment of cystinuria-induced urolithiasis in a knockout mouse model

OBJECTIVE: To assess the effectiveness of L-cystine dimethyl ester (CDME), an inhibitor of cystine crystal growth, for the treatment of cystine urolithiasis in a Slc3a1 knockout mouse model of cystinuria. METHODS: CDME (200 μg per mouse) or water was delivered by gavage daily for four weeks. Higher...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Urology
Egile Nagusiak: Sahota, Amrik, Parihar, Jaspreet S., Capaccione, Kathleen M., Yang, Min, Noll, Kelsey, Gordon, Derek, Reimer, David, Yang, Ill, Buckley, Brian T., Polunas, Marianne, Reuhl, Kenneth R., Lewis, Matthew R., Ward, Michael D., Goldfarb, David S., Tischfield, Jay A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4498569/
https://ncbi.nlm.nih.gov/pubmed/25443947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.urology.2014.07.043
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