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Mass Spectrometry-based in vitro Assay to Identify Drugs that Influence Cystine Solubility

Cystinuria is a rare genetic disorder characterized by recurrent, painful kidney stones, primarily composed of cystine, the dimer of the amino acid cysteine (Sumorok and Goldfarb, 2013). Using a mouse model of cystinuria, we have recently shown that administration of drugs that increase cystine solu...

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Bibliografiske detaljer
Udgivet i:Bio Protoc
Main Authors: Bose, Neelanjan, Zee, Tiffany, Kapahi, Pankaj, Stoller, Marshall L.
Format: Artigo
Sprog:Inglês
Udgivet: Bio-Protocol 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5580967/
https://ncbi.nlm.nih.gov/pubmed/28868331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21769/BioProtoc.2417
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