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Total Synthesis of (−)-Nahuoic Acid C(i) (B(ii))

A convergent total synthesis of (−)-nahuoic acid C(i)(B(ii)) (3), a novel cis-decalin polyketide has been achieved. Key synthetic transformations include Type II Anion Relay Chemistry (ARC) to construct the polyol chain, a Ti-catalyzed asymmetric Diels-Alder reaction to generate the cis-decalin skel...

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Publicat a:J Am Chem Soc
Autors principals: Liu, Qi, Deng, Yifan, Smith, Amos B.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5655813/
https://ncbi.nlm.nih.gov/pubmed/28933833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b08683
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