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Total Synthesis of (−)-Aplaminal
[Image: see text] The total synthesis and assignment of absolute configuration of (−)-aplaminal (1), a cytotoxic metabolite from a sea hare possessing a triazobicyclo[3.2.1]octane skeleton, has been achieved. The synthesis entailed condensation of a monoprotected diamine (3) with dimethyl 2-oxomalon...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2775134/ https://ncbi.nlm.nih.gov/pubmed/18754624 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol801794f |
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