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Enantioselective Total Synthesis of (+)-Peniciketals A and B: Two Architecturally Complex Spiroketals

The enantioselective total syntheses of (+)-peniciketals A and B, two members of a family of architecturally complex spiroketals, has been achieved. Key synthetic transformations comprise Type I Anion Relay Chemistry (ARC) to construct the benzannulated [6,6]-spiroketal skeleton, a Negishi cross-cou...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Deng, Yifan, Yang, Chia-Ping H., Smith, Amos B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8170783/
https://ncbi.nlm.nih.gov/pubmed/33496178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c11424
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