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Total Synthesis of (−)-Nodulisporic Acids D, C and B: Evolution of a Unified Synthetic Strategy
A unified synthetic strategy leading to the total synthesis of (−)-nodulisporic acids D, C, and B is described. Key synthetic transformations include a nickel-chromium mediated cyclization, an aromatic ring functionalization employing a novel copper-promoted alkylation, a palladium-catalyzed cross c...
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| Publicado no: | J Am Chem Soc |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6085755/ https://ncbi.nlm.nih.gov/pubmed/30028603 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b04053 |
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