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Total Synthesis of (−)-Nodulisporic Acids D, C and B: Evolution of a Unified Synthetic Strategy

A unified synthetic strategy leading to the total synthesis of (−)-nodulisporic acids D, C, and B is described. Key synthetic transformations include a nickel-chromium mediated cyclization, an aromatic ring functionalization employing a novel copper-promoted alkylation, a palladium-catalyzed cross c...

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Vydáno v:J Am Chem Soc
Hlavní autoři: Zou, Yike, Li, Xiangqin, Yang, Yun, Berritt, Simon, Melvin, Jason, Gonzales, Stephen, Spafford, Matthew, Smith, Amos B.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6085755/
https://ncbi.nlm.nih.gov/pubmed/30028603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b04053
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