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Structural, physicochemical and dynamic features conserved within the aerolysin pore-forming toxin family

Aerolysin is the founding member of a major class of β-pore-forming toxins (β-PFTs) found throughout all kingdoms of life. PFTs are cytotoxic proteins produced as soluble monomers, which oligomerize at the membrane of target host cells forming pores that may lead to osmotic lysis and cell death. Bes...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Cirauqui, Nuria, Abriata, Luciano A., van der Goot, F. Gisou, Dal Peraro, Matteo
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5654971/
https://ncbi.nlm.nih.gov/pubmed/29066778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-13714-4
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