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Structural, physicochemical and dynamic features conserved within the aerolysin pore-forming toxin family

Aerolysin is the founding member of a major class of β-pore-forming toxins (β-PFTs) found throughout all kingdoms of life. PFTs are cytotoxic proteins produced as soluble monomers, which oligomerize at the membrane of target host cells forming pores that may lead to osmotic lysis and cell death. Bes...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Cirauqui, Nuria, Abriata, Luciano A., van der Goot, F. Gisou, Dal Peraro, Matteo
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5654971/
https://ncbi.nlm.nih.gov/pubmed/29066778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-13714-4
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