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Structural, physicochemical and dynamic features conserved within the aerolysin pore-forming toxin family

Aerolysin is the founding member of a major class of β-pore-forming toxins (β-PFTs) found throughout all kingdoms of life. PFTs are cytotoxic proteins produced as soluble monomers, which oligomerize at the membrane of target host cells forming pores that may lead to osmotic lysis and cell death. Bes...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Cirauqui, Nuria, Abriata, Luciano A., van der Goot, F. Gisou, Dal Peraro, Matteo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5654971/
https://ncbi.nlm.nih.gov/pubmed/29066778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-13714-4
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