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Glucose Directs Amyloid-beta Into Membrane-Active Oligomers

Oligomeric Amyloid-β 1–42 (Aβ-42) peptides are considered to be the most toxic species connected to the occurrence of Alzheimer’s disease. However, not all aggregation conditions promote oligomer formation in vitro, raising the question whether oligomer formation in vivo also requires a specific sui...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Phys Chem Chem Phys
Hauptverfasser: Kedia, Niraja, Almisry, Michael, Bieschke, Jan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5654640/
https://ncbi.nlm.nih.gov/pubmed/28671211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7cp02849k
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