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Beta-barrel models of soluble amyloid beta oligomers and annular protofibrils

Both soluble and membrane-bound pre-fibrillar assemblies of Abeta (Aβ) peptides have been associated with Alzheimer's disease (AD). The size and nature of theses assemblies vary greatly and are affected by many factors. Here we present models of soluble hexameric assemblies of Aβ42 and suggest...

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Detalhes bibliográficos
Main Authors: Shafrir, Yinon, Durell, Stewart R., Anishkin, Andriy, Guy, H. Robert
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976788/
https://ncbi.nlm.nih.gov/pubmed/20830782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22832
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