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Beta-barrel models of soluble amyloid beta oligomers and annular protofibrils

Both soluble and membrane-bound pre-fibrillar assemblies of Abeta (Aβ) peptides have been associated with Alzheimer's disease (AD). The size and nature of theses assemblies vary greatly and are affected by many factors. Here we present models of soluble hexameric assemblies of Aβ42 and suggest...

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主要な著者: Shafrir, Yinon, Durell, Stewart R., Anishkin, Andriy, Guy, H. Robert
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976788/
https://ncbi.nlm.nih.gov/pubmed/20830782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22832
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