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Sleep is bi-directionally modified by amyloid beta oligomers
Disrupted sleep is a major feature of Alzheimer’s disease (AD), often arising years before symptoms of cognitive decline. Prolonged wakefulness exacerbates the production of amyloid-beta (Aβ) species, a major driver of AD progression, suggesting that sleep loss further accelerates AD through a vicio...
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| Publicado en: | eLife |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
eLife Sciences Publications, Ltd
2020
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7360368/ https://ncbi.nlm.nih.gov/pubmed/32660691 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.53995 |
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