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Beta amyloid oligomers and fibrils stimulate differential activation of primary microglia

BACKGROUND: Beta amyloid (Aβ) peptides are the major constituents of the senile plaques present in Alzheimer's diseased brain. Pathogenesis has been associated with the aggregated form of the peptide as these fibrils are the conformation readily found in the plaques. However, recent studies hav...

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Hlavní autoři: Sondag, Cindy M, Dhawan, Gunjan, Combs, Colin K
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2632990/
https://ncbi.nlm.nih.gov/pubmed/19123954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-6-1
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