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β-Amyloid Fibrils Activate Parallel Mitogen-Activated Protein Kinase Pathways in Microglia and THP1 Monocytes

The senile plaques of Alzheimer’s disease are foci of local inflammatory responses, as evidenced by the presence of acute phase proteins and oxidative damage. Fibrillar forms of β-amyloid (Aβ), which are the primary constituents of senile plaques, have been shown to activate tyrosine kinase-dependen...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Neurosci
Egile Nagusiak: McDonald, Douglas R., Bamberger, Maria E., Combs, Colin K., Landreth, Gary E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Society for Neuroscience 1998
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6792680/
https://ncbi.nlm.nih.gov/pubmed/9614222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.18-12-04451.1998
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