A Cell Surface Receptor Complex for Fibrillar β-Amyloid Mediates Microglial Activation

Senile plaques found in the Alzheimer's disease brain are foci of local inflammatory reactions mediated by plaque-associated microglia. The interaction of microglia with compacted deposits of β-amyloid (Aβ) fibrils results in the stimulation of intracellular Tyr kinase-based signaling cascades...

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Bibliografiset tiedot
Julkaisussa:J Neurosci
Päätekijät: Bamberger, Maria E., Harris, Meera E., McDonald, Douglas R., Husemann, Jens, Landreth, Gary E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Society for Neuroscience 2003
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ARTICLE
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6742111/
https://ncbi.nlm.nih.gov/pubmed/12684452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-07-02665.2003
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